New imaging reveals a built-in safeguard that allows B cell populations to rapidly expand in germinal centers without introducing deleterious mutations. Germinal centers are high-speed evolution ...
Cancer does not develop overnight. It can take decades for cancer‐promoting changes in the genome to eventually lead to the formation of a malignant tumor. Researchers at the German Cancer Research ...
After a median follow-up of 10 years, more than one-third of patients with large B-cell lymphoma and nearly half of patients ...
Cancer does not develop overnight. It can take decades for cancer-promoting changes in the genome to eventually lead to the formation of a malignant tumor. Researchers at the German Cancer Research ...
The existing model suggested, improbably, that B cells essentially win the lottery again and again, even while risking everything on the next ticket. "If we're imagining that antibodies get better ...
A cell is fundamentally a container—a vessel that encapsulates life at the most basic level. Many biologists believe encapsulation of chemicals may have been necessary for evolution to gain traction.