Nonsense-mediated mRNA decay (NMD) is a conserved eukaryotic surveillance pathway known to degrade mRNAs containing premature termination codons (PTCs). mRNA recognition by the Upf1, Upf2 and Upf3 NMD ...
Termination of protein translation occurs when the translating ribosome reaches a stop codon that is recognized by a release factor 1,2,3,4. Each of the three stop codons, UAA, UGA and UAG, is used in ...
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